Intern
    THE BRINGMANN GROUP: BIOACTIVE COMPOUNDS FROM NATURE

    Prof. Dr. Dr. h.c. mult. Gerhard Bringmann
    Am Hubland
    97074 Würzburg
    Tel.: +49 931 31 85323
    Fax: +49 931 31 84755
    bringman@chemie.uni-wuerzburg.de


    Secretary's Office:

    Dr. Anette Zillenbiller
    Institut für Organische Chemie
    Am Hubland
    97074 Würzburg
    Tel.: +49 931 31 85322

    Curriculum vitae

    1970-75Study of Chemistry and Biology at the Universities of Gießen and Münster
    1975-78PhD with Prof. Dr. B. Franck, Institut of Organic Chemistry, Münster
    1978-79Post-Doc with Prof. Sir D.H.R. Barton at the Institut de Chimie des Substances Naturelles of the C.N.R.S. in Gif-sur-Yvette, Paris, France
    1984Habilitation, Venia legendi for Organic Chemistry, University of Münster
    1986/87Chairs offered from the Universities of Vienna and Würzburg
    1987-2017Professor (Chair I), Institute of Organic Chemistry, University of Würzburg
    1998Position offered as a director at the Leibniz Institute for Plant Biochemistry in Halle/Saale (turned down)
    2002-2006Liaison Professor ("Vertrauensdozent") of the Fonds der Chemischen Industrie for the University of Würzburg
    2003-2009Liaison Professor of the DFG (German Research Foundation) for the University of Würzburg

    Selected Awards and Honors

    1999Prize for Good Teaching, Free State of Bavaria
    2000Eli Lilly Research Laboratories Lecturer
    2000JSPS Invitation Fellowship for Research in Japan
    2006Adolf-Windaus Lecture and Medal
    2006Doctor honoris causa, Université de Kinshasa (Democratic Republic of the Congo)
    2007Paul-J.-Scheuer Award for Marine Biotechnology
    2008 Honorary Guest Professor, Peking University, Beijing, China
    2012 Doctor honoris causa, Université Catholique du Graben (Democratic Republic of the Congo)
    2012 Member of the European Academy of Sciences and Arts
    2012Médaille du Mérite Civique 1ére Classe (Civic Medal First Class) in Gold of the Congolese People
    2012Doctor honoris causa, Université Officielle de Ruwenzori (Democratic Republic of the Congo)
    2012Honorary Professor, Jinan University, Guangzhou (People's Republic of China)

    2013

    Fellow of the African Academy of Sciences

    2014Gusi Peace Prize
    2015Doctor honoris causa, Université Libre des Pays des Grands Lacs (Democratic Republic of the Congo)
    2016Diplôme de Mérite for Science and Education in the Congo (Association Culturelle Nande, DR Congo)
    2016Diplôme de Reconnaisance de Coopération, Université de Lubumbashi (DR Congo)

    Fields of research

    Organic chemistry, natural products chemistry, with analytical, synthetic, computational, and medicinal facets: Isolation, structural elucidation, total synthesis, biosynthesis, and pharmaceutical development of anti-infective and anti-tumoral agents from nature; hyphenated techniques like HPLC-MS/MS-NMR-CD in combination with quantum-chemical CD calculations; axially chiral biaryls; naphthylisoquinoline alkaloids; chiral porphyrins; materials inspired from nature

    Achievements


    • Group leader/coordinator
     
    2003-2015Speaker and coordinator of the Collaborative Research Centre SFB 630 „Recognition, Preparation, and Functional Analysis of Agents against Infectious Diseases“
    2010-2013Coordinator of the project "Re-installment of Excellence at the University of Kinshasa: Support for the Bachelor’s program" (Foundation Else-Kröner-Fresenius-Stiftung)
    2011-2014Coordinator of the project "Re-installment of Excellence at the University of Kinshasa: Support for the Master’s program" (Foundation Else-Kröner-Fresenius-Stiftung)
    2012-2015          

    Coordinator of the project "The Scholarship System BEBUC, a Unique Concept for the Sustainable Re-installment of Excellence at Congolese Universities" (Else-Kröner-Fresenius-Stiftung)

    since 2015Coordinator of the project "A New Generation of Excellent Professors for the Congo: The Scholarship Program BEBUC" (Else-Kröner-Fresenius-Stiftung)

    • Project leader in further networks - a selection
     
    2004-2012Sonderforschungsbereich (Collaborative Research Centre) SFB 567 „Mechanism of Interspecific Interactions of Organisms“
    since 2009Klinische Forschergruppe (Clinical Research Unit) KFO 216 „Characterization of the Oncogenic Signaling Network in Multiple Myeloma: Development of Targeted Therapies”

    • Decisional member of national and international institutions
    2009-2014 Vice Chairman of the DECHEMA Committee "Low-Molecular Bioactive Compounds"
    2002-2014

    Chairman of the Program Committee of the Annual Irsee Natural Products Meetings ("Irseer Naturstofftage")

    since 2011Member of the International Scientific Committee of Conferences on Chiroptical Spectroscopy
    since 1991 Work and Membership in University Committees (a selection):
    Standing Committee of the University for Strategic Plannings (1991-2013)
    University Senate (2001-2004, and 2009-2015; 2011-2013: Vice Chairman; 2013-2015: Chairman)
    University Council (2009-2015; 2013-2015 Vice Chairman)
    Dean/Vice-Dean of the Faculty (2000-2004)

    • Empowerment: design and initiation of structures
    since 1991Initiator of the Mini-Symposia "Natural Products: Chemistry, Biology, and Ecology" for PhD students, twice per year, involving the Universities of Bayreuth, and Leipzig, the Leibniz Institutes for Plant Biochemistry in Halle and for Natural Product Research and Infection Biology (HKI) in Jena, and the Max-Planck Institute for Chemical Ecology in Jena (more than 50 meetings so far)
    since 2006Initiator and Founding Speaker of the ‘Africa Circle at the University of Würzburg’, with scientists from all ten faculties (today 'Forum Afrikazentrum'; since 2015: Member of the Panel)
    since 2003Initiator of scientific partnership programs and university cooperations with the Université de Kinshasa (2003), with the University of Nairobi (2009), with the Université Catholique du Graben in Butembo (2010), and with 16 further universities, six high-schools, and two primary school in the Congo (2013)
    since 2008Initiator and Head of an Excellence Scholarship Program (BEBUC) in the Congo (presently ca. 180 scholars!)
    since 2009

    Foundation President of the NGO “Support for the University of Kinshasa” (“Förderverein Uni Kinshasa e.V.”)

    since 2014Founding Panel Member of the Bavarian Research Institute of African Studies (BRIAS)

    • Expertise in analytical, synthetic, computational, and medicinal chemistry
    (more than 700 publications and patents)

    Twelve (from a Total of more than 700) Selected Publications from the Major Fields of Research

    1. A. C. Gehrold, T. Bruhn, H. Schneider, U. Radius, D. Schmidt, G. Bringmann; Monomeric Chiral and Achiral Basket-Handle Porphyrins: Synthesis, Structural Features, and Arrested Tautomerism; J. Org. Chem. 2015, 80, 12359-12378.

       

    2. Y. Hemberger, G. Zhang, R. Brun, M. Kaiser, G. Bringmann; Highly Antiplasmodial Non-Natural Oxidative Products of Dioncophylline A: Synthesis, Absolute Configuration, and Conformational Stability; Chem. Eur. J. 2015, 21, 14507-14518.

       

    3. A. C. Gehrold, T. Bruhn, H. Schneider, U. Radius, G. Bringmann; Chiral and Achiral Basket-Handle Porphyrins: Short Synthesis and Stereostructures of These Versatile Building Blocks; Org. Lett. 2015, 17, 210-213.

    4. T. Bruhn, G. Pescitelli, S. Jurinovich, A. Schaumlöffel, F. Witterauf, J. Ahrens, M. Bröring, G. Bringmann; Axially Chiral BODIPY DYEmers: An Apparent Exception to the Exciton Chirality Rule; Angew. Chem., Int. Ed. 2014, 53, 14592-14595; Axial-chirale BODIPY-DYEmers: eine offensichtliche Ausnahme für die Exciton-Chiralitäts-Methode; Angew. Chem. 2014, 126, 14821-14824.

    5. T. Bruhn, F. Witterauf, D. C. G. Götz, C. T. Grimmer, M. Würtemberger, U. Radius, G. Bringmann; C,C- and N,C-Coupled Dimers of 2-Aminotetraphenylporphyrins: Regiocontrolled Synthesis, Spectroscopic Properties, and Quantum-Chemical Calculations; Chem. Eur. J. 2014, 20, 3998-4006.

       

    6. Y. Hemberger, J. Xu, V. Wray, P. Proksch,  J. Wu, G. Bringmann; Pestalotiopens A and B: Stereochemically Challenging Flexible Sesquiterpene-Cyclopaldic Acid Hybrids from Pestalotiopsis sp.; Chem. Eur. J. 2013, 19, 15556-15564.

       

    7. G. Bringmann, B. K. Lombe, C. Steinert, K. N. Ioset, R. Brun, F. Turini, G. Heubl, V. Mudogo; Mbandakamines A and B, Unsymmetrically Coupled Dimeric Naphthylisoquinoline Alkaloids, from a Congolese Ancistrocladus Species; Org. Lett. 2013, 15, 2590-2593.

       

    8. E. C. Tatsis, A. Schaumlöffel, A. C. Warskulat, G. Massiot, B. Schneider, G. Bringmann; Nudicaulins, Yellow Flower Pigments of Papaver nudicaule: Revised Constitution and Assignment of Absolute Configuration; Org. Lett. 2013, 15, 156-159.

       

    9. G. Bringmann, G. Zhang, T. Büttner, G. Bauckmann, T. Kupfer, H. Braunschweig, R. Brun, V. Mudogo; Jozimine A2: The First Dioncophyllaceae-Type Naphthylisoquinoline Dimer, with Three Chiral Axes and High Antimalarial Activity; Chem. Eur. J, 2013, 19, 916-923.

       

    10. A. Schaumlöffel, M. Groh, A. Speicher, G. Bringmann; Stereochemical Assignment of Cyclic Bisbibenzyl by HPLC-CD on a Chiral Phase and Quantum-Chemical CD Calculations; Eur. J. Org. Chem. 2012, 6878-6887.

       

    11. L. Liu, T. Bruhn, L. Guo, D. C. G. Götz, R. Brun, A. Stich, Y. Che, G. Bringmann; Chloropupukeanolides C–E, Cytotoxic Pupukeanane Chlorides with a Spiroketal Skeleton from Pestalotiopsis fici; Chem. Eur. J. 2011, 17, 2604-2613 (with Cover Picture).

       

    12. G. Bringmann, T. Gulder, T. A. M. Gulder, M. Breuning; Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products; Chem. Rev. 2011, 111, 563-639.

       

    Kontakt

    Lehrstuhl für Organische Chemie I
    Am Hubland
    97074 Würzburg

    Tel.: +49 931 31-85322
    Fax: +49 931 31-84755
    E-Mail

    Suche Ansprechpartner

    Hubland Süd, Geb. C1