
Prof. Dr. Dr. h.c. mult. Gerhard Bringmann
Lehrstuhl für Organische Chemie I
Am Hubland
97074 Würzburg
Tel.: +49 931 31 85323
Fax: +49 931 318 4755
Email: bringman@chemie.uni-wuerzburg.de
Secretary's Office:
Anette Zillenbiller
Institut für Organische Chemie
Am Hubland
97074 Würzburg
Tel.: +49 931 31 85322
Curriculum vitae
26.08.1951 | Born in Münster/Germany |
1970-75 | Study of Chemistry and Biology at the Universities of Gießen and Münster |
1975-78 | PhD with Prof. Dr. B. Franck, Institut of Organic Chemistry, Münster |
1978-79 | Post-Doc with Prof. Sir D.H.R. Barton at the Institut de Chimie des Substances Naturelles of the C.N.R.S. in Gif-sur-Yvette, Paris, France |
1984 | Habilitation, Venia legendi for Organic Chemistry, University of Münster |
1986/87 | Chairs offered from the Universities of Vienna and Würzburg |
since 1987 | Professor (Chair I), Institute of Organic Chemistry, University of Würzburg |
1998 | Position offered as a director at the Leibniz Institute for Plant Biochemistry in Halle/Saale (turned down) |
2002-2006 | Liaison Professor ("Vertrauensdozent") of the Fonds der Chemischen Industrie for the University of Würzburg |
2003-2009 | Liaison Professor of the DFG (German Research Foundation) for the University of Würzburg |
Selected Awards and Honors
1999: | Prize for Good Teaching, Free State of Bavaria |
2000: | Eli Lilly Research Laboratories Lecturer |
2000: | JSPS Invitation Fellowship for Research in Japan |
2006: | Adolf-Windaus Lecture and Medal |
2006: | Doctor honoris causa, Université de Kinshasa (Democratic Republic of the Congo) |
2007: | Paul-J.-Scheuer Award for Marine Biotechnology |
2008: | Honorary Guest Professor, Peking University, Beijing, China |
2012: | Doctor honoris causa, Université Catholique du Graben (Democratic Republic of the Congo) |
2012: | Member of the European Academy of Sciences and Arts |
2012: | Médaille du Mérite Civique 1ére Classe (Civic Medal First Class) in Gold of the Congolese People |
2012: | Doctor honoris causa, Université Officielle de Ruwenzori (Democratic Republic of the Congo) |
2012: | Honorary Professor, Jinan University, Guangzhou (People's Republic of China) |
Fields of research
Organic chemistry, natural products chemistry, with analytical, synthetic, computational, and medicinal facets: Isolation, structural elucidation, total synthesis, biosynthesis, and pharmaceutical development of anti-infective and anti-tumoral agents from nature; hyphenated techniques like HPLC-MS/MS-NMR-CD in combination with quantum-chemical CD calculations; axially chiral biaryls; naphthylisoquinoline alkaloids; chiral porphyrins; materials inspired from nature
Achievements
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since 2003 | Speaker and coordinator of the Collaborative Research Centre SFB 630 „Recognition, Preparation, and Functional Analysis of Agents against Infectious Diseases“ |
since 2010 | Coordinator of the project "Re-installment of Excellence at the University of Kinshasa: Support for the Bachelor’s program" (Foundation Else-Kröner-Fresenius-Stiftung) |
since 2011 | Coordinator of the project "Re-installment of Excellence at the University of Kinshasa: Support for the Master’s program" (Foundation Else-Kröner-Fresenius-Stiftung) |
since 2012 | Coordinator of the project "The Scholarship System BEBUC, a Unique Concept for the Sustainable Re-installment of Excellence at Congolese Universities" (Else-Kröner-Fresenius-Stiftung) |
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2004-2012 | Sonderforschungsbereich (Collaborative Research Centre) SFB 567 „Mechanism of Interspecific Interactions of Organisms“ |
since 2009 | Klinische Forschergruppe (Clinical Research Unit) KFO 216 „Characterization of the Oncogenic Signaling Network in Multiple Myeloma: Development of Targeted Therapies” |
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since 2009 | Chairman of the DECHEMA Committee "Low-Molecular Bioactive Compounds"; |
since 2002 | Chairman of the Program Committee of the Annual Irsee Natural Products Meetings ("Irseer Naturstofftage");
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Work and Membership in University Committees (a selection): | |
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since 1991 | Initiator of the Mini-Symposia "Natural Products: Chemistry, Biology, and Ecology": Natural Products Chemistry Workshops for PhD students, twice per year, involving the Universities of Bayreuth, Leipzig, Bonn, and Vienna, the Leibniz Institutes for Plant Biochemistry in Halle and for Natural Product Research and Infection Biology (HKI) in Jena, and the Max-Planck Institute for Chemical Ecology in Jena (more than 40 meetings so far) |
2006-2009 | Initiator and Founding Speaker of the ‘Africa Circle at the University of Würzburg’, with scientists from all ten faculties (today 'Forum Afrikazentrum') |
2003-2012 | Initiator of scientific collaborations, partnership programs, and official university cooperations with the Université de Kinshasa (UNIKIN, 2003), with the University of Nairobi (2009), with the Université Catholique du Graben (UCG) in Butembo (2010), and with six further universities, and three high-schools and one primary school in the Congo (2012) |
since 2008 | Initiator and Head of an Excellence Scholarship Program (BEBUC) in the Congo (presently 69 scholars!) |
since 2009 | Foundation President of the NGO “Support for the University of Kinshasa” (“Förderverein Uni Kinshasa”) |
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(more than 660 publications and patents) | |
Twelve (from a Total of ca. 660) Selected Publications from the Major Fields of Research
- G. Bringmann, D. Goetz, T. Bruhn
Comprehensive Chiroptical Spectroscopy (N. Berova, P. Polavarapu, K. Nakanishi, R.W. Woody, Eds.), Vol. 2, John Wiley & Sons, 2012, pp. 355-420.
The Online Stereoanalysis of Chiral Compounds by HPLC-ECD Coupling in Combination with Quantum-Chemical Calculations. - C. Brückner, D.C.G. Götz, S.P. Fox, C. Ryppa, J.R. McCarthy, T. Bruhn, H.W. Daniell, S. Banerjee, P. Daddario, M. Zeller, R.W. Boyle, G. Bringmann
J. Am. Chem. Soc. 2011, 133, 8740-8752
Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins. - L. Liu, T. Bruhn, L. Guo, D.C.G. Götz, R. Brun, A. Stich, Y. Che, G. Bringmann
Chem. Eur. J. 2011, 17, 2604-2613 (with cover picture)
Chloropupukeanolides C–E, Cytotoxic Pupukeanane Chlorides with a Spiroketal Skeleton from Pestalotiopsis fici. - G. Bringmann, T. Gulder, T.A.M. Gulder, M. Breuning
Chem. Rev. 2011, 111, 563-639
Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products. - G. Bringmann, T. Gulder, B. Hertlein, Y. Hemberger, F. Meyer
J. Am. Chem. Soc. 2010, 132, 1151-1158
Total Synthesis of the N,C-Coupled Naphthylisoquinoline Alkaloids Ancistrocladinium A and B and Related Analogues. - M. Xu, T. Bruhn, B. Hertlein, R. Brun, A. Stich, J. Wu, G. Bringmann
Chem. Eur. J. 2010, 16, 4208-4216 (with cover picture)
Shuangancistrotectorines A-E, Dimeric Naphthylisoquinoline Alkaloids with Three Chiral Biaryl Axes, from the Chinese Plant Ancistrocladus tectorius. - G. Bringmann, T. Bruhn, K. Maksimenka, Y. Hemberger
Eur. J. Org. Chem. 2009, 2717-2727
The Assignment of Absolute Stereostructures through Quantum Chemical Circular Dichroism Calculations. - A. Ponte-Sucre, T. Gulder, A. Wegehaupt, C. Albert, C. Rikanovic, L. Schäflein, A. Frank, M. Schultheis, M. Unger, U. Holzgrabe, G. Bringmann, H. Moll
J. Med. Chem. 2009, 52, 626-636
Structure-Activity Relationship and Studies on the Molecular Mechanism of Leishmanicidal N,C-Coupled Arylisoquinolinium Salts. - G. Bringmann, D.C.G. Götz, T.A.M. Gulder, T.H. Gehrke, T. Bruhn, T. Kupfer, R. Radacki, H. Braunschweig, A. Heckmann, C. Lambert
J. Am. Chem. Soc. 2008, 130, 17812-17825
Axially Chiral ß,ß‘-Bisporphyrins: Synthesis and Configurational Stability Tuned by the Central Metals. - G. Bringmann, J. Mutanyatta-Comar, M. Knauer, B.M. Abegaz
Nat. Prod. Rep. 2008, 25, 696-718
Knipholone and Related 4-Phenylanthraquinones: Structurally, Pharmacologically, and Biosynthetically Remarkable Natural Products. - G. Bringmann, T.F. Noll, T.A.M. Gulder, M. Grüne, M. Dreyer, C. Wilde, F. Pankewitz, M. Hilker, G.D. Payne, A.L. Jones, M. Goodfellow, H.-P. Fiedler
Nature Chem. Biol. 2006, 2, 429-433
Different Polyketide Folding Modes Converge to an Identical Molecular Architecture. - G. Bringmann, A.J. Price Mortimer, P.A. Keller, M.J. Gresser, J. Garner, M. Breuning
Angew. Chem. 2005, 117, 5518-5563; Angew. Chem. Int. Ed. 2005, 44, 5384-5427
Atroposelective Synthesis of Axially Chiral Biaryl Compounds.
